The bit that worries me is that we're going to go from the 'normal' process to millions in a very short time. Usually there is time to spot if something was missed in trials but this time it's big bang.
On an entirely selfish level I see no scenario where I'll be vaccinated before the mid to late summer. I'm not uncomfortable with that.
That said, as soon as my partners parents and my close friend fighting cancer are vaccinated I can relax. Don't want to be the one to infect somebody else and kill them.
Will be interesting to see the point at which things do get a lot better. Once you have the most vulnerable and medical staff vaccinated you'd think we can start opening things up as the death rates should plummet. Things won't be 'normal' but I'd really like to think by March/April time we can have most things open, even if with restrictions.